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If HAART (Highly Active Antiretroviral Therapy) can work so well, then why does treatment failure happen? Achieving and maintaining a low viral load requires maintaining a certain level of HIV drugs in the body. Poor treatment adherence — missing doses or failing to take medications as prescribed — can lower the level of anti-HIV drugs to the point that the virus resumes rapid multiplication. Poor adherence to therapy may also allow HIV to develop resistance to anti-HIV medications. When this happens, viral load goes up and CD4 cell counts can go down, signaling treatment failure.
Successfully adhering to your treatment regimen by taking the correct dose of each of your anti-HIV drugs every day is the most important thing you can do to control HIV and prevent treatment failure. If you have trouble taking or remembering any of your anti-HIV drugs, talk to your healthcare provider right away.
Patients should read the Patient Information, including "What is the most important information I should know about Truvada?". It is important that you discuss your treatment options and any questions that you may have with your healthcare provider.
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